Buy Generic Celebrex (Celecoxib) 100, 200 mg online

Last Updated on February 19, 2017 by Dr.Derek Fhisher

Most popular brand: Celebrex
Active ingredient: Celecoxib
Available dosage forms: 100, 200 mg

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Celecoxib general information

Using Exubera requires routine excursions to the doctor to make certain wholesome lung function. Let patient rest following the treatment.6. Actually many physicians treat chronic pain together with the exact same drugs used in the treatment of depression. It has shown in a single study in California to lessen pain in addition to the famous drug celecoxib.

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Skin reaction is among the most frequent reactions related with these drugs. In spite of the severity of its own toxicity, particularly with chronic usage, there is barely any information concerning the side effects of NSAIDs. Selective NSAIDs can decrease pain as well as inflammation whilst lowering the danger of gastric ulceration. This medication is, in addition, used as a treatment for high blood pressure (hypertension). An allergy to sulfa drugs too can worsen asthma as a result of its influence on the lungs. There are not any particular skin or blood tests accessible to diagnose sulfa allergy.

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CELECOXIB (celecoxib)

When administered to adult dose is 200 mg / day in 1 – 2 admission, if necessary – on 200 mg 2 times / day.

elderly patients weighing less than 50 kg or with moderate hepatic dysfunction treatment should be started with a minimum recommended dose.

Clinical experience of celecoxib in patients with severely impaired hepatic or renal function is not.

Cardio – vascular system: often – peripheral edema; sometimes – worsening of arterial hypertension, increased blood pressure, arrhythmias, hot flashes, palpitations, tachycardia; rarely – a manifestation of congestive heart failure, ischemic stroke and myocardial infarction.

From the digestive system: often – abdominal pain, diarrhea, dyspepsia, flatulence, teeth (alveolar post-extraction alveolitis) disease; sometimes – vomiting; rarely – gastric and duodenal ulcers, esophageal ulceration, intestinal perforation, pancreatitis, elevated liver enzymes; there are reports – gastro – intestinal bleeding, hepatitis, hepatic failure.

From the central and peripheral nervous system: often – dizziness, increased muscle tone, insomnia; sometimes – restlessness, drowsiness; rare – confusion, hallucinations, aseptic meningitis.

From the urinary system: often – urinary tract infection; there are reports – acute renal failure, interstitial nephritis.

The respiratory system: often – bronchitis, cough, pharyngitis, rhinitis, sinusitis, upper respiratory tract infection.

Dermatological reactions: often – itching, skin rash; sometimes – alopecia, rash; there are reports – photosensitivity, skin peeling (including the syndrome and erythema multiforme Stevens – Johnson), toxic epidermal necrolysis, acute generalized exanthematous pustulosis.

From the hematopoietic system: sometimes – anemia, ecchymosis, thrombocytopenia.

From the senses: sometimes – ringing in the ears, blurred vision; rare – loss of taste, loss of smell.

From the reproductive system: has been reported – menstrual disorders.

Allergic reactions: , rarely – angioedema, bullous eruption; there are reports – anaphylaxis, vasculitis.

From the side of the body as a whole: often – exacerbation of allergic diseases, flu-like syndrome, accidental injury.

Contraindications

Severe renal dysfunction, severe hepatic dysfunction; an allergic reaction to acetylsalicylic acid or other NSAIDs in history, III trimester of pregnancy, lactation (breastfeeding); hypersensitivity to sulfonamides, hypersensitivity to celecoxib.

Pregnancy and breastfeeding

There are no adequate and well-controlled studies safety of celecoxib during pregnancy has not been conducted, therefore use is not recommended.

If necessary, use during lactation should decide the issue of termination of breastfeeding.

The experimental research is not revealed toxic effect on the fetus; It shows that animals celecoxib concentration in human milk is similar to that in plasma.

Application for violations of liver function

is contraindicated in severe hepatic dysfunction.

Application for violations of renal function

is contraindicated in severe renal impairment.

The use in elderly patients

elderly patients weighing less than 50 kg or with moderate hepatic dysfunction treatment should be started with a minimum recommended dose.

Caution should be used in patients with heart failure and other conditions predisposing to fluid retention. Use in patients with gastric ulcer or duodenal ulcer in is possible only in case of complete remission of the disease; with severe renal and hepatic failure – only in exceptional cases.

Clinical experience of celecoxib in patients with severely impaired hepatic or renal function, and in patients younger than 18 years, is not.

In an application with drugs that inhibit the activity of CYP2C9 isoenzymes, including fluconazole possibly significant increase in the plasma concentration of celecoxib. Antacids (aluminum and magnesium) reduce the degree of absorption of celecoxib of 10%, which does not cause clinically significant effects. With simultaneous use of celecoxib with warfarin increases the risk of bleeding.

Materials for Specialists in avtivnomu substance “Celecoxib» 2