Last Updated on February 19, 2017 by Dr.Derek Fhisher

Atarax Hydroxyzine 25, 10 mg
Most popular brand: Atarax
Active ingredient: Hydroxyzine
Available dosage forms: 25, 10 mg
buynow
Purchase Hydroxyzine without a prescription or Generic Atarax from 500mg.org and get excellent drug on reduced international prices. To buy Hydroxyzine online is to have considerably more privacy than what’s accessible when taking a prescription to a pharmacy that is local. 500mg.org gives you the possibility to purchase affordable Hydroxyzine 25, 10 mg online and also find out more about Hydroxyzine side effects, dosage information and drug interactions. Ask your pharmacist any questions you might have relating to Hydroxyzine, particularly if it’s new to you. Buy generic Atarax online at the best affordable cost from 500mg.org and get your Hydroxyzine tablets sent at your doorstep in time. Having the ability to buy Hydroxyzine online or have other prescriptions filled online saves time, effort, and the expense of a long excursion. They have the power to compare prices more easily when people purchase Hydroxyzine online. By comparison, the best on-line sources for prescription drugs like Hydroxyzine frequently have extensive drug info right on the site, so consumers can get answers for their questions quickly and easily when they purchase Hydroxyzine 25, 10 mg online, and they can easily print out the advice for future reference. However, accessibility to an authorized pharmacist is a phone call away when folks buy Hydroxyzine online with trustworthy online sources.

Hydroxyzine general information

Sometimes hives is brought on by health concerns like lupus or thyroid disease. The ideal eczema treatment relies upon somebody’s age, overall health status, and also the type and asperity of the disease. The precise source of eczema isn’t yet known but it is regarded the cause is regularly genetic. This type of skin hives is rather common out of all the different types of chronic urticaria. Such an eczema is frequently an allergic reaction to something someone has touched, including topical medicines. There are many other symptoms which are non skin related too.

It’s not recommended to use aged models of filters as it may cause some problems too rather than a cure. Nevertheless, you need to be aware of the few potential side effects which come with the products. These stones can vary from pea gravel size to the size of the grain of sand.

Too little sleep may be brought on by several factors, not just those related to your own health. This is the reason it is vital to look for the advice of your physician if you think you have IBS as there may be other potentially more severe causes. Although some severe instances of depression may take a pharmaceutical approach, many instances of depression might be successfully addressed through natural methods. Consequently, addressing the total well-being of the body is an excellent beginning step toward treating the depression.

People, who withstand sinusitis, will need to look at having humidifiers to help reduce the sinusitis symptoms. A person with hives might have extra hives symptoms depending on what’s triggering the hives. It’s very secure and used along with antihistamines can lower the need for corticosteroids. Cold medicines might help suppress symptoms, but the cold virus proceeds to roam in the body.

Symptoms for example itchy penis skin, redness as well as inflammation which don’t subside daily or so ought to be seen by a physician to establish the precise cause. You’re much more inclined to have a bladder infection than either of both of the other conditions mentioned previously because bladder infections are really so common. The individual will urinate into a certain drug testing cup. The symptoms are quite straight forward.

It’s known that people afflicted by depression have low degrees of serotonin. Now on the surface it would seem perfectly all-natural to employ a drug that raises the human body’s own all-natural sleep aid to treat insomnia. There are really no known long-term side consequences. Relaxation Technique is an additional kind of therapy where an individual is taught just how to cope with strain and anxiety and in addition with a number of the physical anxiety.

The fatty acids found in fish oil have a lot of benefits for the total wellness of the body, including cardiovascular added benefits, anti-inflammatory properties, plus skin health. 1 combination that is employed well may be the mix of above supplements together with mangosteen juice, which is a wonderful antioxidant. You might also reap the benefits of additional calcium if you really do not consume lots of calcium rich foods. Taken internally, this is among the very best breast herbs. Chemotherapy is another sort of therapy.

In case you have a pet or go through the unpleasant feelings connected with hay fever you might want to look at a OTC medicine for your own allergy symptoms. They’ll not merely keep track of your own vital signs but will likewise supply you with the medication that can assist you through painful withdrawal symptoms. Benzodiazepines offer instant relief.

Atarax (Hydroxyzine)

There are contraindications. Before taking consult your doctor.

The commercial name abroad (abroad) – Hizin, Hidroxina, Hydroze, Masmoran, Neurax, Orgatrax, Otarex, Vistaject, Vistaril.

Currently, the analogues (generics) of the drug in pharmacies of Moscow is not for sale!

All tranquilizers (anxiolytics) here.

All the drugs used in neurology and psychiatry, here.

Ask a question or leave a review about the medicine (please do not forget to specify the name of the drug in the body of the message) here.

Preparations containing Hydroxyzine (Hydroxyzine, ATC (ATC code) N05BB01):

Common forms of release (more than 100 proposals in Moscow pharmacies)

Atarax (Hydroxyzine) – instructions for use. Prescription drug information is intended only for healthcare professionals!

Clinico – pharmacological group:

Mode of action

diphenylmethane derivative, has a moderate anxiolytic activity; also has sedative, antiemetic, antihistamine, and m – anticholinergic action. Does central m – cholinergic and histamine H1 – receptors and inhibits the activity of certain subcortical areas. It does not cause mental dependence and addiction. The clinical effect after 15 – 30 minutes after ingestion of the drug.

It has a positive influence on cognitive abilities, improves memory and attention. It relaxes skeletal and smooth muscles, has a bronchodilator and analgesic effects, a moderate inhibitory effect on gastric secretion. Hydroxyzine reduces the itching in patients with urticaria, eczema and dermatitis. Chronic administration were observed cindroma cancellations and deterioration of cognitive functions. Polysomnography in patients with insomnia and anxiety demonstrates lengthening the duration of sleep, reduce the frequency of nighttime awakenings after single or repeated administration of hydroxyzine at a dose of 50 mg. Reduced muscular tension in patients with anxiety observed while taking the drug at a dose of 50 mg 3 times a day.

Pharmacokinetics

Hydroxyzine highly absorbed from the gastrointestinal tract. Cmax observed after 2 hours after taking the drug.

After a single dose of the drug in a single dose of 25 mg or 50 mg in adults in the plasma concentration is 30 ng / ml and 70 ng / ml, respectively.

Oral bioavailability and / m the introduction of 80%.

Hydroxyzine more concentrated in the tissues (including the skin) than in plasma. The distribution coefficient is 7 – 16 l / kg.

Hydroxyzine penetrate the BBB and placental barrier, concentrating mainly in fetal tissues than in the mother. The metabolites are found in breast milk.

Metabolism and excretion

Hydroxyzine is metabolized in the liver. The major metabolite (45%) – cetirizine, which is a blocker of histamine H1 – receptors. Hydroxyzine total clearance of 13 ml / min / kg. T1 / 2 in adults is 14 hours. Only 0.8% of Hydroxyzine is excreted unchanged in the urine.

Pharmacokinetics in special clinical situations

In children, the total clearance is 4 times less than in adults, T1 / 2 children under the age of 14 years is 11 hours, in children aged 1 year – 4 hours.

In elderly patients T1 / 2 of 29 hours, the distribution ratio is 22.5 L / kg.

in patients with impaired liver function T1 / 2 is increased up to 37 h, the concentration of metabolites in serum is higher than in young patients with normal liver function. The antihistamine effect may persist for 96 hours.

Indications for use of the drug Atarax ®

  • adults: for the relief of anxiety, agitation, feelings of inner tension, irritability with neurological, psychiatric (including generalized anxiety, adjustment disorder) and somatic diseases, chronic alcoholism; abstinence syndrome in chronic alcoholism, accompanied by psychomotor agitation;
  • as a sedative during premedication;
  • itchy skin (as a symptomatic therapy).

Dosage

The drug is taken orally.

For the symptomatic treatment of pruritus in children aged 12 months to 6 years, the drug is administered in a daily dose of 1 – 2.5 mg / kg body weight in divided doses; children over 6 years of age – a dose of 1 – 2 mg / kg / day in divided doses.

For sedation medication for children is prescribed in a dose of 1 mg / kg body weight for 1 hour prior to surgery, as well as an additional night before the operation.

For adults for symptomatic treatment of anxiety is prescribed in doses of 25 – 100 mg per day in divided doses during the day or at night. An average dose of 50 mg per day (morning, 12.5 mg, 12.5 mg and 25 mg day at night). If necessary, the dose may be increased to 300 mg per day.

for the symptomatic treatment of pruritus initial dose is 25 mg, if appropriate dose may be increased 4 times (25 mg four times a day).

The maximum single dose should not exceed 200 mg, the maximum daily dose is not more than 300 mg.

In elderly patients the initial dose should be reduced by 2 times.

Patients with renal failure secondary to severe, as well as with hepatic impairment dose reduction is necessary.

Side effects

The side effects associated with anticholinergic effects: rarely (mainly in elderly patients) – dry mouth, urinary retention, constipation, accommodation.

From the CNS: drowsiness, weakness (especially at the beginning of treatment), headache, dizziness. If the weakness and drowsiness do not disappear after a few days of therapy, the drug dose should be reduced. Very rarely (if a large overdose) – tremors, convulsions, disorientation.

Cardio – vascular system: hypotension, tachycardia.

From the digestive system: nausea, changes in liver function tests.

Others: increased sweating, allergic reactions, fever, bronchospasm.

When using the drug at the recommended doses were observed clinically significant respiratory depression. Spontaneous motor activity (including very rare cases of tremor and seizures), disorientation observed at large overdose.

Side effects observed when taking the drug Atarax ®, usually mild, transient and disappear after a few days from the beginning of treatment or after dose reduction.

Contraindications to the use of the drug Atarax ®

  • porphyria;
  • pregnancy;
  • during labor;
  • lactation (breastfeeding);
  • hypersensitivity to the drug;
  • Hypersensitivity to cetirizine and other piperazine derivatives, aminophylline or ethylenediamine.

Not recommended to prescribe pills Atarax ® patients with hereditary galactose intolerance and malabsorption of glucose and galactose since in the tablets include lactose.

Caution should be prescribed the drug in infants, prostatic hyperplasia with clinical symptoms, difficulty urinating, constipation, with an increase in intraocular pressure, dementia, tendency to seizures; with predisposition to arrhythmia; while the use of drugs with arrhythmogenic effect; together with other means, oppressive central nervous system, or holinoblokatorami (requires dose reduction). Requires dose reduction in patients with severe renal impairment or moderate, with liver failure, in elderly patients with a decrease in glomerular filtration rate.

Use of the drug Atarax ® Pregnancy and breastfeeding

Atarax ® contraindicated during pregnancy, during labor and delivery.

If you need to use Atarax during lactation should stop breastfeeding.

Application for violations of liver function

Patients with hepatic impairment dose reduction is necessary.

Application for violations of renal function

Patients with renal failure secondary to severe dose reduction is necessary.

Cautions

When the need for allergy tests Atarax intake should be discontinued 5 days before the study.

Patients taking Atarax ®, should refrain from drinking alcohol.

Effects on ability to drive vehicles and management mechanisms

Patients taking Atarax ®, if necessary driving and mechanisms should be warned that the drug can affect the concentration of attention and speed of psychomotor reactions.

Overdose

Symptoms: increased anticholinergic effects, depression or paradoxical CNS stimulation, nausea, vomiting, involuntary motor activity, hallucinations, impaired consciousness, arrhythmia, hypotension; rarely – tremors, convulsions, disorientation that occur when a large overdose.

Treatment: if spontaneous vomiting is absent, you must call it by artificial means or to gastric lavage. Carry out general measures aimed at maintenance of the vital functions of the body, and the monitor observation of the patient before the disappearance of symptoms of intoxication in the next 24 hours.

In the case of need for vasopressor effect of norepinephrine or appointed metaramenol. Do not use epinephrine. There is no specific antidote. The use of hemodialysis is ineffective.

Drug Interactions

Atarax ® potentiates the effect of drugs which depress the central nervous system, such as opioids, barbiturates, tranquilizers, sleeping pills, ethanol (if combinations require individual selection of doses of drugs).

Atarax ® while the application prevents the pressor effect of epinephrine (adrenaline) and anticonvulsant activity of phenytoin and prevents the action of betahistine and cholinesterase blockers.

In an application Atarax ® It does not affect the activity of atropine, belladonna alkaloids, cardiac glycosides, antihypertensives, histamine H2 – receptors.

Avoid joint appointment Atarax with MAO inhibitors and holinoblokatorami.

Hydroxyzine inhibitor is isozyme CYP2D6 and when used in high doses can cause interactions with substrates of CYP2D6. As hydroxyzine is metabolized in the liver, can be expected to increase its concentration in the blood when coadministered with inhibitors of liver enzymes.

of the pharmacies vacation Terms

The drug is released with a prescription.

Conditions and terms

The drug should be stored out of reach of children, dry place at temperatures no higher than 25 ° C. Shelf life – 5 years.

  • Buy Generic Hydrea (Hydroxyurea) 500 mg onlineBuy Generic Hydrea (Hydroxyurea) 500 mg online Most popular brand: Hydrea Active ingredient: Hydroxyurea Available dosage forms: 500 mg Purchase Hydroxyurea without a prescription or Generic Hydrea from 500mg.org and get superb drug on reduced international costs. To purchase Hydroxyurea online […]
  • Buy Generic Asacol (Mesalazine) 400 mg onlineBuy Generic Asacol (Mesalazine) 400 mg online Most popular brand: Asacol Active ingredient: Mesalazine Available dosage forms: 400 mg Buy Mesalazine without a prescription or Generic Asacol from 500mg.org and get excellent drug on reduced global costs. To buy Mesalazine online would be to have […]
  • Buy Generic Compazine (Prochlorperazine) 5 mg onlineBuy Generic Compazine (Prochlorperazine) 5 mg online Most popular brand: Compazine Active ingredient: Prochlorperazine Available dosage forms: 5 mg Purchase Prochlorperazine without a prescription or Generic Compazine from 500mg.org and get exceptional drug on reduced global prices. To purchase […]
  • Buy Generic Avandia (Rosiglitazone) 2, 4, 8 mg onlineBuy Generic Avandia (Rosiglitazone) 2, 4, 8 mg online Most popular brand: Avandia Active ingredient: Rosiglitazone Available dosage forms: 2, 4, 8 mg Buy Rosiglitazone without a prescription or Generic Avandia from 500mg.org and get superb drug on reduced international prices. To purchase Avandia online […]