Last Updated on February 19, 2017 by Dr.Derek Fhisher
Most popular brand: Dramamine
Active ingredient: Dimenhydrinate
Available dosage forms: 50 mg
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Dimenhydrinate general information
The consequences of dimenhydrinate are extremely much like those of diphenhydramine hydrochloride. 8-Chlorotheophylline was added to be able to counteract drowsiness. Alcohol might increase drowsiness and dizziness as long as you are taking dimenhydrinate. Frequent medications for nausea and vomiting along with ginger are frequently used in pregnancy.
Acute intoxication of the drug happens when somebody takes from 750-1250 mg simultaneously. Psychiatric patients could also abuse dimenhydrinate to accomplish an anti-anxiety effect. This medication is utilized to prevent and treat motion sickness, vomiting, dizziness brought on by motion sickness, including nausea and vomiting connected with various conditions like chemotherapy, radiation, and surgery. This side effects are reported by at least 1% of people employing this medication. This drug might not mix well with several other drugs. The abuse of dimenhydrinate also contributes to temporary amnesia after intervals of prolonged use as it decreases the sum of acetycholine in the entire body.
Several things can impact the dose of medication that someone needs, like body weight, other health conditions, and other medications. It could be harmful that people use this medication if their doctor hasn’t prescribed it. Tell your physician about all medicines which you are taking, nor take any medicine unless your physician approves. Also, some forms of the medication might not be used for most of the conditions discussed here.
Take dimenhydrinate carefully as instructed by your doctor. Talk with your pharmacist about the appropriate disposal of your own medication. Your pharmacist might be able to counsel you on managing side consequences. Don’t stop employing this medication without consulting your own doctor. If your physician has recommended a dose different from those listed here, don’t alter the way which you are using the medication without consulting your own doctor. If you get pregnant when taking this medication, contact your physician immediately.
It is usually utilized to lower the effects of idiopathic vestibular syndrome. The sedation due to diphenhydramine, however, is substantially stronger compared to the stimulation brought on by 8-chlorotheophylline, so the total effect remains mostly sedating. Gravol is employed to prevent and treat motion sickness along with nausea and vomiting related to various conditions like chemotherapy, radiation, and surgery. This medication is employed to prevent and treat motion sickness in addition to nausea and vomiting related to various conditions like chemotherapy, radiation, and surgery. Other, less serious side effects can be more probable to occur.
An interaction between two medications doesn’t always mean you must stop taking one of these. Speak to your doctor about any side impact that seems unusual or that’s especially bothersome. Don’t offer this medication to anybody else, even if they got the exact same symptoms as you do. Side effect or health problem isn’t better or you’re feeling worse. If you believe there was really an overdose, call the local poison control center or ER straight away.
In case you have heart disease, speak with your doctor. When you have glaucoma, speak with your doctor. Check all drugs you’re taking with your physician. When you have not discussed this with your own doctor or aren’t sure why you’re using this medication, speak to your own doctor. Inform your doctor in case your condition will not improve or whether or not it worsens. Call your physician for assist with any side results.
Before beginning using Gravol Tablets, be certain to inform your doctor of any healthcare conditions or allergies you might have, any medications you’re taking, whether you’re pregnant or breast-feeding, and any other major facts about your own health. Before you start using a medication, make certain to inform your doctor of any healthcare conditions or allergies you might have, any medications you’re taking, whether you’re pregnant or breast-feeding, and any other major facts about your own health. It is very important to use this medication carefully as recommended by your physician or pharmacist. It’s crucial that you keep a written list of every one of the prescription and nonprescription (over-the-counter) medicines you’re taking, and any products like vitamins, minerals, or alternative dietary supplements. There’s no FDA guidance on the utilization of Dimenhydrinate with regard to specific gender populations. It is likewise important info to carry together with you in case of emergencies.
Some side effects could be serious. This medication is mainly taken as needed. Don’t take two doses of the medication. Don’t take more than 400 mg of the medication in a single day. Don’t combine Dramamine with several other drugs that have diphenhydramine. Dimenhydrinate may cause negative effects.
Analogues drug dimenhydrinate – Pliva
treatment for motion sickness – H1 – blocker histamine receptors
Mode of action
blocker H1 – histamine receptors. Has antiemetic, sedative, central anticholinergic, local anesthetic effect, depresses the central nervous system, weaken the effects of vestibular stimulation, acting primarily on the otoliths, in high doses – semicircle on TV.
The sea and air sickness (prophylaxis), Meniere’s disease, vestibular and labyrinth disorders.
Hypersensitivity; children’s age (up to 1 year); Pregnancy, lactation. Angle-closure glaucoma (including predisposition to it), open-angle glaucoma, prostatic hyperplasia with clinical manifestations, urinary retention (including predisposition), bladder neck obstruction, bronchial asthma.
From the nervous system: excessive fatigue or weakness, decreased ability to concentrate, headache, dizziness, anxiety, nervousness, somnolence, insomnia (especially in children), rarely – the weakening of the night and color vision, disturbance of accommodation
With the respiratory system:. dryness of mucous membranes of the nose and throat, thickening of bronchial secretions
From the CCC. : lowering blood pressure, arrhythmia
Allergic reactions:. urticaria, angioedema, bronchoconstriction
Other:. difficulty urinating.
Application and dosage
Inside, and food, adults – 50 – 100 mg 2 – 3 times a day for children aged from 1 year to 6 years – 12.5 – 25 mg 3 times a day for children from 7 to 12 years – 25 – 50 mg 3 times a day
to prevent sea or air sickness -. 50 – 100 mg 30 minutes before the trip. The maximum daily dose for adults – 300 – 400 mg.
antiemetic effect of the drug may mask the symptoms of acute appendicitis or poisoning medicinal drugs.
In the period of treatment must be careful when driving and other lesson. Potentially hazardous activities that require high concentration and psychomotor speed reactions.
dampening effect on the central nervous system sedatives, hypnotics, antidepressants, ethanol; the effect of anticholinergic drugs.
It may mask the symptoms of hearing loss when combined with ototoxic antibiotics and leads to irreversible hearing loss.
It may reduce the effectiveness of apomorphine prescribed as an emetic drug in case of poisoning.