Last Updated on February 19, 2017 by Dr.Derek Fhisher
Most popular brand: Imitrex
Active ingredient: Sumatriptan
Available dosage forms: 25, 50, 100 mg
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Sumatriptan general information
Symptoms commonly develop in the spring as well as fall. What may have each of the symptoms of the cluster headache may in reality be something entirely different. Eyestrain is another typical cause. The 2nd characteristic could be the cyclical feature of the cluster headache.
Tiredness, dehydration and also a low blood glucose can all really play their part too. Or, if something you’re eating isn’t inducing the headaches, it may be making them much more painful. Additionally It is vitally crucial that you healing wounds, muscular function, sleep, growth and wholesome pregnancy. For instance, some women love aromatherapy but might not know that a few oils (ie rosemary) can’t be properly used when pregnant.
Not everyone is a great candidate for lasik surgery though. Additionally, There are some pharmaceutical choices for cluster headache treatment. There’s an oral form of the drug available but it’s not regarded as effective as injectable sumitriptan. It really is because unlike other types of treatment, botox doesn’t involve using scalpels and surgical procedures.
Speak with your doctor in the event you gain weight after you begin taking your prescription. Check with your own doctor on another treatment option. Muscle relaxants and anti-psychotic drugs also have been effective in some instances. While the levels receive a lot higher and lower, the true fluctuation of the hormones is really not as pronounced as it can certainly be every time a woman isn’t pregnant.
There are various several types of headaches and within this guide, we’re going to discuss a few of them. Furthermore, they may be effective for a sustained time period, which is, in addition, important for all those people whose migraines can endure for days as opposed to hours. Although there are a few options available for treatment not they all may work. This solution is a strong decongestant and among the most common nasal congestion remedies.
There are numerous medicines that could hurt your even chances of really being a fantastic candidate for lasik surgery. Many lasik doctors won’t do the surgery if you’re taking Imitrex. These do not demand a prescription. In all these cases, I didn’t have a genuine headache.
Cluster Headaches aren’t common and terribly painful. Secondary headache means the headache is really a symptom of another disease or process. The definitive source of cluster headaches isn’t well understood, but might involve abnormalities of the hypothalamus. Cluster headaches aren’t common.
Stress is among the major factors which can add to the onset of the migraine. Individuals with tension headaches could also have problems with malady, throbbing or a sensation of tightness within the head. In contrast to popular belief, tension headache isn’t necessarily caused by emotional stress, but instead, like migraine, probably as an effect of the neurochemical process inherent within the brain of the headache sufferer. In case your usual migraine is with aura, they’re likely to carry on.
You might get annoyed by the migraine malady, and you might be desperate to consider anything to relieve your pain. For those who have taken Meridia for quite a while, please don’t stop taking it suddenly without speaking to your doctor first. You must always be open regarding the medicines you’re taking. Don’t hesitate to get in touch with your doctor.
Imitrex is a favorite medicine used mainly to take care of migraine headaches. Neurontin is a strong drug that could have serious side effects concerning kidney, liver as well as heart disease. Beta-blockers like Propranolol and anti-depressants like Elavil have proven to work. Naproxen 500mg is affordable and prescription only.
Should you be planning to eventually become pregnant, now may be the time to see your physician to sort out medication for your own migraines prior to, during and following the infant is born when you might be breast-feeding. If you receive a terrible headache, see your doctor since this can be a symptom of pre-eclampsia which requires quick treatment. You must avoid aspirin as soon as the birth draws near as it could exacerbate bleeding. Headaches from allergies are due to irritations connected with flowers, pollen, in addition to your body’s response to particular foods.
The triptans are a type of drug that is chemically much like serotonin, that’s itself a neurotransmitter that is deemed to play part in causing migraines. Several drugs for preventing migraine have been developed lately, including serotonin antagonists which mimic the action of the important brain chemical. Even though these new drugs are shown to work oftentimes of migraine there are a number of studies which suggest that they’re more effective for migraine sufferers who lack skin sensitivity. If they’re followed by means of a migraine headache, the customary migraine medications may be prescribed by your Doctor.
Migraine treatment can are available in various forms. Feverfew and reflexology also needs to be avoided. Pain relievers like aspirin, paracetamol and ibuprofen are generally utilised to ease symptoms. Nearly all patients with cluster headache might be controlled on medication.
Sumatriptan (Sumatriptan) – instructions for use
International name: Sumatriptan
Structure and Composition
The tablets, film-coated white or almost white, round, biconcave; in cross section the core or white almost white. 1 tablet contains 50 mg sumatriptan. Excipients . lactose monohydrate – 92 mg, microcrystalline cellulose – 9 mg, povidone – 3.6 mg colloidal silicon dioxide – 1.8 mg, sodium croscarmellose – 1.8 mg of magnesium stearate – 1.8 mg.
The composition of the coating film: Valium – 3 mg of talc – 1 mg, titanium dioxide – 0.55 mg macrogol 4000 – 0.45 mg.
in blisters or plastic pot 2, 4, 6 or 10 tablets. Packaged in a cardboard box.
The tablets, film-coated 100 mg. The multiples of 2, 4, 6 or 10 tablets.
An agonist of serotonin 5 – HT1 – receptors. Preparation with protivomigrenoznoy activity
The pharmacological action of the drug sumatriptan
The agent for the treatment of migraine; agonist of serotonin 5 – HT 1 – receptors. The therapeutic effect is due to sumatriptan, on – apparently, by two mechanisms: the substance excites serotonin 5 – HT 1 – vascular smooth muscle receptors of the carotid artery system and causes their constriction. The carotid arteries supply blood to the tissues of the head, including meninges; with the expansion of blood vessels of the brain membranes is associated with a migraine. In addition, sumatriptan activates receptors endings of afferent fibers of the trigeminal nerve in the dura, resulting in reduced release of sensory neuropeptides. Sumatriptan poorly crosses the BBB and according to the experiments does not have proper analgesic properties.
sumatriptan effect generally occurs within 30 minutes after ingestion, and after 10 – 15 min after the s / c administration.
Indications for use drug sumatriptan
Migraine (mild asthma, with or without aura).
Hypersensitivity, hemiplegic, basilar or oftalmoplegicheskaya forms of migraine, ischemic heart disease (including suspected it), angina pectoris (including Prinzmetal angina), myocardial infarction (also in history), hypertension (uncontrolled), peripheral arterial occlusive disease, stroke or transient ischemic attack (including history), liver and / or kidney failure.
Dosage and method of use
To the relief of migraine oral dose is 100 mg once daily; sometimes can be an effective dose of less than 100 mg; in the event of renewed attacks possible readmission, and the daily dose should not exceed 300 mg. P / K is administered in a dose of 6 mg; if necessary repeat injection of the same dose can be performed not earlier than 1 hour after the first administration; the maximum daily dose of n / a – 12 mg.
When Horton syndrome injected s / c at a dose of 6 mg once daily during an attack; the maximum daily dose – 12 mg; interval between injections for at least 1 h.
CNS: dizziness, weakness, drowsiness.
Cardio – vascular system: hypotension and transient increase in blood pressure, tachycardia or bradycardia.
From the digestive system: nausea, vomiting.
Dermatological reactions: skin rash, erythema, pruritus.
Local reactions: at the s / c infusion – short-term pain at the injection site.
Other: a feeling of warmth, tingling, pain, pressure or compression in different parts of the body.
Application of pregnancy and breastfeeding
Clinical experience with sumatriptan during pregnancy is limited, and therefore contraindicated.
Caution should be used during lactation. It is not recommended to breastfeed for 24 hours after taking sumatriptan.
Application for violations of liver function
To use caution in the human liver.
Application for violations of renal function
To use caution in renal impairment.
Use of the drug in children
Safety and effectiveness in children and adolescents under the age of 18 years has not been established.
Cautions when receiving drug sumatriptan
Not for migraine prophylaxis (introduction during a migraine aura before the others. Symptoms can not prevent the development of headache). Patients at risk from cardiovascular therapy does not begin without the prior survey (in postmenopausal women, men over the age of 40 years, those with coronary artery disease risk factors). In the appointment during lactation is not recommended to breastfeed for 24 hours after taking sumatriptan. In patients with hypersensitivity to sulfonamides when administered sumatriptan there is an increased risk of allergic reactions (from cutaneous manifestations to anaphylactic shock). If there is no effect on the administration of the first dose should clarify the diagnosis. Experience in the use of sumatriptan in patients over 65 years is limited (no significant differences in the pharmacokinetics compared to younger patients is not observed).
Before the appointment of sumatriptan in patients with newly diagnosed migraine or atypical flowing to exclude others. Potentially dangerous neurological diseases. It must be borne in mind that patients with migraine are at risk of stroke or transient ischemic attacks. Following intranasal administration of sumatriptan may experience pain and tightness in the chest. The pain can be intense and radiate to the neck. If there is reason to believe that these symptoms are a manifestation of coronary artery disease, it is necessary to conduct a survey. During the period of treatment must be careful when driving and other lesson. Potentially hazardous activities that require high concentration and psychomotor speed reactions.
Interactions with other medicinal products
In an application with lithium salts cases of serotonin syndrome are described.
In an application with moclobemide increases the bioavailability of moclobemide in the absence of clinical manifestations.
In an application with the risk rizatriptanom additive hyperstimulation serotonin 5 – HT 1 – receptors; with ergotamine – may develop vascular spasm.
With the simultaneous use of grass St. John’s wort preparations may increase serotonergic effects and the development of side effects.
Use of the drug sumatriptan only on prescription, instructions are given for reference!
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