Last Updated on February 19, 2017 by Dr.Derek Fhisher

Zanaflex Tizanidine 2, 4 mg
Most popular brand: Zanaflex
Active ingredient: Tizanidine
Available dosage forms: 2, 4 mg
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Tizanidine general information

Muscle relaxants for example Tizanidine, and massaging sore muscles may also help. Over-the-counter muscle relaxer medications incorporate a group of various drugs that may be purchased sans the prescription from a health expert. In the event, MS impacts the facial nerve, an individual may experience numbness on any aspect of the face. This results in the skin to redden and dilate, resulting in excessive sweating. Methocarbamol and chlorzoxazone, common ingredients of several skeletal muscle relaxants, can cause harmless color shifts in the individual’s urine. Additionally It is observed that if a tiny volume of sertraline goes to the baby through breastfeeding, it might result in a few serious complications.

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Instructions for use of the drug tizanidine

tizanidine medication from the group of muscle relaxants. Assigned to patients suffering from muscle pain, as well as having a number of diseases.

At first I used only in neurological diseases, but because of its analgesic properties, has been used by patients with headache, neuropathic pain and a variety of musculo – skeletal pain.

In most cases it prescribes to patients complaining of low back pain or hernia.

Mode of action

Tizanidine affects increased muscle tone, making it smaller and thus relieves spasms. In addition, it has no effect on skeletal muscle.

It has an analgesic effect and reduces the manifestations of both chronic and acute pain.

The pharmacokinetics of medicines

The tablets are absorbed very quickly, which is confirmed by tests – is literally an hour later the drug appears in the blood. Displays the drug is excreted in the urine.

Indications for use

This drug is given:

  • for painful muscle spasms associated with functional spinal cord injuries;
  • Multiple Sclerosis;
  • after surgery for osteoarthritis or herniated disc;
  • in chronic myelopathy;
  • after stroke;
  • in degenerative diseases of the spinal cord and spasms of central origin.

The hidden danger of medicines

There are reasons for receiving tizanidine may be unsafe.

  • severe liver disease and kidney;
  • idiosyncrasy of the drug;
  • age (children of the drug is not prescribed);
  • Pregnancy and lactation;
  • pills with fluvomeksaminom.

The mechanism of action

tizanidine stimulates alpha2 – adrenergic receptors and thereby inhibits the release of amino acids that stimulate the NMDA – receptors.

Because – for this at the level of the spinal cord neuronal excitation transfer polisinapticheskie suppressed. Moreover, the drug has no effect on monosynaptic reflex and skeletal muscle.

Instructions for use

doctors recommend to read the instructions before use tizanidine. The drug is available as tablets and capsules.

Dosage and method of use of the drug, depending on the disease and the concomitant neglect of the disease.

The initial dose is 2 mg. In this case the effect of the drug occurs within a few hours after administration, and ends in about 6 hours.

Therefore, the interval between doses should be 6-7 hours. Gradually, the dosage can be increased to 4 mg. In rare cases, the daily dose of the drug may be 36 mg.

Patients suffering from various diseases of the kidneys or liver, should be very careful to take this medication. In addition, be sure to consult with your doctor.

The first time should pay attention to health after taking the drug. If it gets worse, then you need to reduce the dose of medication.

Overdose and the additional guidance

To relieve muscle spasms, tizanidine should be taken in the form of tablets of 2 mg 3 or 4 times a day.

When the patient is spastic muscle condition, the dose should be installed doctor individually. In no case can not exceed the daily rate of the drug – 36 mg.

As for the capsule, then the beginning of treatment daily dose should not exceed 6 mg. that is, the patient can take only one capsule. The maximum rate at which reception can be increased, it is still 6 mg.

When taking medication can appear side signs. Most often, patients feel nausea, dizziness, drowsiness and weakness. It is also observed decreases in blood pressure and indigestion.

If you use drugs with antihypertensive drugs can occur bradycardia and hypotension. It is necessary to consult a doctor if after taking the drug the patient felt:

  • the pain in his right side;
  • loss of appetite;
  • very tired;
  • increase in muscle spasms.

The drugs should not be taken during pregnancy or lactation. And if not taking the medicine can not do, then breast-feeding should be discontinued.

Also, you can not take medication with alcohol because it may increase drowsiness. Caution should be taken to the drug, patients older than 65 years.

Children of the drug are virtually absent, and doctors do not recommend, at least up to 18 years.

Patients who suffer from renal failure, must reduce the dose. Also, extreme caution is necessary to take the tablets, patients with heart disease.

If the same drug at the reception there is poor health, it should be discontinued immediately.

It is not recommended to use the drug before driving a car.

If there was a drug overdose, it will be the first symptoms: vomiting, drowsiness and, in extreme cases, coma. At home, the doctors recommend the use of activated carbon.

If poisoning symptoms persist and intensify, it is necessary to seek medical help.

What do they think about the product specialists and patients

Reviews of patients who were taking tizanidine and physicians.

This drug should be administered only in cases of severe pain, as after it can seriously disrupt the work of some bodies. First of all, suffer from liver, kidney and stomach.

Despite the fact that many drug contraindications, I do not doubt its effectiveness.

Headaches and muscle pain, multiple sclerosis, nerve pathology – he copes with all these problems. Moreover, it is proved by thousands of patients.

I, probably, the drug is not suitable. Almost immediately after the reception became much dizzy and nausea. I thought that the body gets used and everything goes, but then the problems started with the stomach. I had to ask the doctor to replace the medicine.

I bought a vehicle, since the aggravation of cervical syndrome began, and tizanidine when – that the doctor prescribed. There were some side effects, such as fatigue and low blood pressure. The main thing is that the drug helped.

After spinal surgery for a long time I did not take strong drugs, but once the pain returned. He rushed to the hospital where the doctor prescribed tizanidine. I took it at night and in the morning there was a miracle – all gone! Nothing hurts, and no unpleasant symptoms. That’s the way.

I am a sportsman, so they often suffer from a herniated disc. The doctor has written tizanidine, but warned that there may be sleep disturbances, and so on. D. In general, it should be taken only as a last resort, but it really helps to relieve the pain.

Tips for the reception of patients

It is best to start taking this medicine with small doses, because you never know how to react to his body. By the way, cease abruptly it is not necessary to drink, too.

Since the drug is very causes drowsiness, then you can use it sometimes as a sleep aid.

I have had a lot of “pobochek”, so I do not recommend drinking this medication for a reason. Speaking of “a lot”, I mean that I had almost all the features of the poisoning.

Pros and cons of experience

The benefits of the drug lies in the fact that he really effectively helps at strong muscular pains.

Patients mark its therapeutic properties primarily in osteochondrosis and intervertebral hernia.

Cons – in a large number of contraindications. Even those with excellent health sometimes complain that after taking this medicine, there are various disruption of the body.

Therefore, we must not only listen to your doctor and read the instructions for use.

Cheap and cheerful

The drug is available in several variations. The most common – a tablet with 2, 4 and 6 mg. The package of 30 pieces generally. There is also a drug in capsules – 6 mg, 10 pieces per pack.

Price tizanidine about 100 to 150 USD.

The drug should be stored out of the reach of small children and at a temperature no higher than 25 ° C. Usually the drug shelf life of no more than 3 years. For sale only by prescription.

substitute medication

The USA analogue of tizanidine – Sirdalud.

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